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By Nikki Cabus

A Small Startup with Big Backing is Betting it can Fix Clinical Trials and has Issued a Challenge to Find Out

Read Time 4 Minutes

Modern Trials®, a startup aiming to transform clinical trial-patient matching, is collaborating with leading healthcare technology provider InterSystems® by issuing a challenge to assess Modern Trials’ EHR-based recruitment relative to current recruitment methods.

Co-founded in 2019 by Dr. Christopher Ochner, Modern Trials aims to match patients with clinical trials that could potentially save their life by connecting patients in need of advanced treatment options through democratizing access to clinical trials. They ingest the healthcare organization’s patient data and then make it searchable for their life science customers, clinical trial managers, in a private and secure manner.

Modern Trials is preparing a $2.4M NIH grant application that requires a healthcare organization partner with clinical trials to execute a Data Use Agreement to test grant aims.The challenge will be a head-to-head comparison to see which method results in more enrollees, more enrollees in traditionally underrepresented groups, more representative samples, and higher completion rates. Financial compensation will be provided to the partner healthcare organization.

“Grants like this are vital to provide the support necessary to determine, with real world data, the best method of democratizing access to advanced therapeutics. Until now, fewer than 15% of patients in need have had access to such opportunities,” Dr. Christopher Ochner told South Florida Tech Hub.

“Modern Trials extends its gratitude to South Florida’s Tech Hub’s ongoing support as we aim to bring these opportunities to all patients no matter who or where they are.”

The Advanced Research Projects Agency for Health (ARPA-H), an agency within the U.S. Department of Health and Human Services (HHS), announced October 2023 that it will take action to improve the nation’s ability to conduct clinical trials safely, quickly, and equitably and to improve clinical trial access for people in communities across the country as the first initiative within the recently launched ARPANET-H Health Innovation Network.

The goal of Advancing Clinical Trial Readiness (ACTR) is to enable 90% of all eligible Americans to take part in a clinical trial within a half hour of their home. To do so, ACTR will leverage the nationwide capabilities and reach of the ARPANET-H Customer Experience Hub by pursuing activities with a diverse array of stakeholders in order to advance, integrate, and extend clinical trial capabilities that overcome challenges in evaluating new technologies, therapies, and platforms.

“Clinical trials are essential to evaluating potentially life-saving breakthroughs and getting them to patients, including in times of rapid response, such as during national emergencies,” said ARPA-H Director Renee Wegrzyn, Ph.D.

“The Advancing Clinical Trial Readiness initiative activates the ARPANET-H health innovation network as we work with organizations from across the country to advance technologies and insights to create a robust national clinical trial infrastructure.”

Working together with patient volunteers, clinical trials help researchers understand what treatments work, gathering a variety of data to help identify better ways to improve patients’ health. Yet many challenges in conducting clinical trials are slowing the speed at which new treatments can get to patients, such as lack of interoperability across electronic health records, enrollment processes that can lead to non-representative study populations, complex study protocols, lack of access to people living in certain parts of the United States, and the myriad and inconsistent variables involved in running trials in real-world settings, or the cost in running trials in controlled settings.

ACTR will work with groups across the country, including innovators, industry, patients, academia, hospital centers, community health centers, and non-traditional partners, such as retail pharmacies or home health innovators, to build faster, less expensive trials with decentralized processes. The effort will also build trials that operate closer to, or at, points of care and are representative of our nation’s geography, age, gender, race, ethnicity, and socioeconomic groups.

“Recent advances in technologies, including artificial intelligence, digital health technologies, and machine learning — along with open standards — enable new opportunities to increase the speed, improve access, and expand the diversity of clinical trials,” said ARPA-H Resilient Systems Mission Office Director Jennifer Roberts, Ph.D.

“Through this effort, we want to develop novel innovations to distribute common protocols across many more locations so that we can change the current paradigm and open the door to faster, cheaper, and more representative trials.”

Modern Trials offers a strong business justification for data use under the auspice of a National Institute of Health (NIH) grant project. Formal security review, Data Use Agreement (DUA), and Broad Agency Announcements (BAAs) will stipulate that data will be used only to complete project aims and destroyed upon completion (1.5-2y).

Some of the partnership requirements are:

  • Healthcare system with at least 1M patient records in their electronic health record system
  • 1,000 active clinical trials
  • Systems located anywhere throughout the United States

With millions actively seeking answers, Modern Trials is on a mission to connect patients with the life-changing potential of clinical trials. Modern Trials is betting it can fix clinical trials!

Click here for more information on the Modern Trials Challenge and NIH Proposal Partnership Details.

By Adam Elitzur

Modern Trials and InterSystems Collaborate to Transform Clinical Trial Recruitment

Read Time 5 Minutes

Modern Trials®, a startup aiming to transform clinical trial-patient matching, is now collaborating with leading healthcare technology provider InterSystems®.

Currently, clinical trial recruitment is accomplished by either relying on doctors to refer the patients they think will meet trial eligibility criteria or by patients responding to a trial advertisement. Neither of these methods are very effective, as there are over 50,000 active clinical trials that each have very specific eligibility criteria. The collaboration between Modern Trials and InterSystems aims to solve this issue.

 

The Birth of Modern Trials

Founded in 2019 by Dr. Christopher Ochner and Dr. Alexander Logsdon, Modern Trials aims to match patients with clinical trials that could potentially save their life by connecting patients in need of advanced treatment options through democratizing access to clinical trials.”

Dr. Logsden, a practicing clinician often experienced his patients desperately seeking, but unable to find, appropriate clinical trial opportunities. Dr. Ochner had been working in research administration, running clinical trials and noticed companies spending tons of money trying to promote these trials and desperate to find patients. The two parties were continuously missing each other.

Dr. Ochner had the unfortunate experience of his own mother, Mae, being diagnosed with stage IV cancer. After frantically searching for clinical trials that were both clinically relevant and immediately available, he continuously come up empty handed. Dr. Ochner had to find her a clinical trial fast and rightfully assumed it would be easy because he works in the field. Unfortunately, that wasn’t the case.

“I spent a month and I couldn’t get it done for my own mother,” Dr. Ochner told South Florida Tech Hub. “And that’s having been in the industry 20 years. I said to my Co-Founder Logsdon, “You were right, this system is broken and we need to fix it.”

That was the birth of the Miami-based Modern Trials.

Modern Trials sits at the intersection of health care and life science, partnering with healthcare organizations who have the patients in need of additional treatment options. They ingest the healthcare organization’s patient data and then make it searchable for their life science customers, clinical trial managers, in a private and secure manner.

 

How can InterSystems help?

InterSystems delivers high performance, cloud- first data platforms that solve data interoperability, speed, and scalability problems for large organizations globally through unifying disparate data into a single, complete view to enable better business outcomes. InterSystems’s IRIS for Health – Community Edition enables interoperability between EHRs and health applications, which enables utilization of data across distributed systems. This product arguably makes InterSystems the mac daddy of EHR data integration. What is EHR data integration you ask?

Modern Trials needs to search for patients who meet specific trial eligibility criteria (sometimes 50 or more) from EHR data. This data comes from many different healthcare organizations which means it comes in different formats and structures, and uses different standards, units, conventions and terms. However, for that data to be useful, it must be all made completely uniform. This monumental task is a major challenge when trying to utilize health records from different sources, particularly at scale with millions of records.

It’s incredibly complex and the reason that getting your medical records where and when you or your provider need them seems impossible. InterSystems IRIS for Health – Community Edition is built to do exactly this. Modern Trials will use it to ingest very large amounts of data from different sources (and therefore in disparate formats, structures, etc.) so that it winds up neatly and uniformly formatted on their database. This enables their customers to search that data and get accurate results. Ochner states; “For Modern Trials, this is key; it makes it possible to query this data so the right patients can be found and presented with potentially life-saving opportunities.”

InterSystems, a provider of next-generation data solutions that support mission-critical applications and drive digital transformation, has been the information engine powering some of the world’s most important applications in business, government and healthcare since the 1970’s. Some of their largest healthcare customers are Epic and the US Department of Veterans Affairs. Their products have received global industry recognition from Forrester, Gartner and KLAS Research and they have a 45-year history in the digital health sector working with the largest and most successful providers, payers, health networks, and health IT companies in the world. In fact, InterSystems is the world’s most popular data platform for healthcare, with more patient records managed on its technology than any other company. Of particular relevance to Modern Trials, InterSystems has an expansive network of EHR data and numerous healthcare organization clients that could benefit from clinical trial matching services.

The collaboration between Modern Trials and InterSystems aims to solve the previously insurmountable issue of bringing the right patients together with the right trial opportunities, largely facilitated by the EHR data integration enabled by InterSystems. “When we go through all the EHR data, we can pre-screen people without having to bother them,” Ochner explained. “This way we go directly to the individual and we already know that they’re very likely to meet criteria. About 96% of patients want to hear about it. They really appreciate having relevant opportunities brought right to them.”

The collaboration provides benefits for both companies. “InterSystems has a huge footprint in the healthcare space and a sizable but smaller footprint in the life science space,” Ochner stated. “Modern Trials sits right at the intersection of health care and life science and this collaboration illustrates the utility of InterSystems technology for life science customers. Their technology enables us to do what we do so this collaboration will also showcase how Modern Trials enables healthcare organizations to provide advanced treatment options to their patients. We are grateful for the opportunity to demonstrate to InterSystems the value in providing trial recruitment services to their clients through Modern Trials.”

An innovation like Modern Trials, paired with a trusted player in healthcare informatics like InterSystems, could revolutionize the trial recruitment process, potentially solving the most expensive pain point in the therapeutic approval process. This would increase access to new medications and medical devices for patients in need, and reduce the time and cost associated with bringing new therapeutics to market. Ultimately, Modern Trials and InterSystems hope to accomplish the mission of providing the opportunity for a better and longer life to every patient in need.

By Nikki Cabus

FAU Tech Runway announces Venture Class 11 companies

Read Time 6 Minutes

FAU Tech Runway® just announced the 20 companies accepted into the 11th cohort of its Venture Program.

The Venture Program provides the most promising startups and talented entrepreneurs in South Florida with an opportunity to join a year-long program that offers resources from FAU’s Innovation and Business Development pipeline, entrepreneurial instruction, structured team-based mentoring, networking, marketing and capital-raising assistance, co-working space, events, intern support, and other vital programs. This program will run February – December

Companies accepted into the Venture Program must have strategic alignment with FAU’s research focus areas, including drone technologies; educational technologies; environmental science; marine science; ocean engineering; neuroscience; healthy aging; big data analytics; artificial intelligence; machine learning; cyber security; sensing; and smart systems.

“The program has been a tremendous help in many founders’ journeys, and when we joined the program, we were a one-person company with an idea,” stated Saida Florexil, Venture Class 8 alumnus and Co-Founder & CEO of Imanyco, a company aiming to improve communication accessibility for people with hearing loss.

“By the time we graduated, we had built a team, and a product, raised funds, and we were able to work with some of the world’s largest companies. The mentorship, resources, and support that we received were incredibly valuable to our journey.”

At Tech Runway, experts have created a program that harnesses and directs the entrepreneurial spirit, providing a complete ecosystem for forward-thinking entrepreneurs, innovative students, faculty, alumni and the community. Program participants receive more than $100,000 in resources and services, including but not limited to mentoring, entrepreneurial education, introductions to early-stage capital, pitch practice opportunities, networking, co-working space and much more. Applications are opened twice a year to be accepted into the Venture Program.

Jessica Beaver, Associate Director of FAU Tech Runway, told South Florida Tech Hub that as the region continues to grow as national leader for tech and business that they have seen more of a need for startup resources as startups flock to the area.

“Due to a high demand, FAU Tech Runway has committed to providing our area two cohorts each year versus only one. This is the second cohort of the year allowing us to serve 40 companies, doubling the amount of startups served in previous years.”

From smart sensors to a fitness app to a decorative planter box company, this cohort has it all. “We are excited about the mix of students, faculty, and community in this cohort and the interesting combination of both SaaS-based and physical products.”

Jessica also noted that they have seen an influx in AI-driven startups. “It’s certainly becoming more prevalent as the tech industry continues to transform. AI is becoming more and more of a common trend with the companies that apply.”

Venture Class 11 participants joined a robust community of fellow entrepreneurs, mentors, investors, instructors and top-level support professionals. They have a lot of work ahead of them, but having the right community supporting them is the best first step. FAU Tech Runway® is a public-private partnership formed to incubate and accelerate early-stage technology-based companies, under the purview of FAU’s Division of Research. Applications for the next cycle of the Venture Program will open on March 3.

The 20 companies in Venture Class 11 are:

  • ADAM Rehabilitation sells dynamic performance braces and expert-level training services to individuals with full functional abilities or disabilities, to help them achieve safer and stronger joints.
  • AskDaddysaurus is a media-based avatar targeted at new parents to provide fun, engaging and accessible childcare content to save time and energy, increase efficiency and build confidence as a new caregiver.
  • AskTakeGo Inc (ATG) is a startup based in Fort Lauderdale, engaged in the development of software for the heavy construction equipment industry.
  • Carevocacy is a learning platform aimed at the elderly population that provides 1:1 online tutoring and classes that address social determinants of health, bridge the digital literacy gap, and offer opportunities to be competitive in the workplace.
  • Enchanted Wave is a Florida-based tech startup that has developed a brainwave-sensing headband and its companion mobile apps for research use, in the field of sleep and cognitive studies and sport performances.
  • EpiPaws is developing epigenetic biomarkers for age and health to improve pet healthcare and increase pet longevity. Its first product, the Pet Age Test, estimates age in dogs and cats from a simple mouth swab.
  • Esther.ai is a cloud-based Artificial Intelligence (AI) application that will disrupt the application development market. Esther.ai’s objective is to reduce testing time and budget from weeks to hours post-development.
  • Fair Witness Technologies (a DBA of ANV Services LLC) offers a self-authenticating digital document format that is the core element of an integrated ecosystem of technology tools. This new, open-source format creates persistent authenticity.
  • Fitnessatyourdoor is a software as a service (SaaS) marketplace that matches trainers and clients and uses data to make recommendations to both parties to improve their results.
  • K Executive Solutions Inc. is a virtual assisting agency that helps business owners and busy professionals streamline their administration tasks, handling the busy work so clients can focus on what matters the most to them.
  • MedAI/SmartBioSense has developed an AI-driven decision support system that helps build a model to understand how well we can predict mortality, ICU admission, and mechanical ventilation for patients hospitalized with COVID-19.
  • Modern Trials Inc. partners with health care organizations and leverages electronic health care data to identify patients in need of advanced treatment options and match them with appropriate clinical trial opportunities.
  • My Autoimmune LLC empowers individuals with autoimmune conditions to take ownership of their health and well-being using holistic methods. It connects individuals with a trusted network of holistic health professionals and evidence-informed research.
  • Parking Genie provides an innovative peer-to-peer business concept to revolutionize how consumers park cars and store boats. Through a digital listing, homeowners can create passive income and customers can search – then pay in advance – for parking.
  • Primary AI is building a patient-centric data-sharing ecosystem in health care and medicine. Its primary goal is to bridge the gap between patients, providers and scientific research.
  • RaiseLink provides startups and startup ecosystem partners with instant matching based on personalized algorithms. Education, business planning and feedback features enhance user engagement, keeping data fresh and accurate.
  • RedeLit’s mission is to redefine literature to help people fall in love with reading, learn how to write/read in a fun way, and bring an increase to literacy percentages in the USA – and the world – so people have a better quality of life.
  • ScreenPlanter LLC is a decorative planter box for horizontal beams of screen enclosures. No tools are required as the company uses ScreenExtender™ brackets. Boxes measuring 2 feet, 4 feet, 6 feet, or a Corner ScreenPlanter™ are available.
  • Show Agents connects overbooked realtors to local licensed showing assistants that can show properties on their behalf, similar to that of Uber for realtors.
  • SyncData Inc. is a compliance tech SaaS company that automates compliance norms like ISO’s with the use of AI.

Pete Martinez, Founder and Chairman of RaiseLink, an intelligent platform for investors and startups, is one of the recently accepted Venture Class 11 cohort members. Although a long time techie and former IBM executive, Pete still understood the importance of programs like FAU Tech Runway.

“We felt it was critical that we walk in the shoes of the startup and go through all the education a startup goes through. FAU’s Venture Program is providing great insight which will in turn make us and our platform even better.”

For more information on FAU Tech Runway®, visit techrunway.fau.edu.

By Riley Kaminer

Entrepreneurs and investors come together at sold-out Pitch and Pour event in Coral Gables

Read Time 4 Minutes

It was an evening of innovation, entrepreneurship, and networking at South Florida Tech Hub’s Pitch and Pour event on August 25th in Coral Gables.

Hosted by angel investor Tahl Milburn, the Investment Sub-Committee Chair of Tech Hub’s Startup Committee, at Merrick Manor, upwards of 55 people from the South Florida tech scene came to meet each other and discuss the opportunities present in our rapidly-growing ecosystem.

“It is a pleasure to have you all here, as we gather in one of the world’s most exciting tech ecosystems,” Milburn said in his opening remarks.

Startup founders were at the core of the event. These eight entrepreneurs had the opportunity to pitch their company to some of South Florida’s top investors. They each had three minutes to showcase their startup, followed by three minutes of questions, before moving onto the next investor. Community members were able to listen in on pitches as they were happening. All the while, there were ample networking opportunities, facilitating connections between startups and key local stakeholders.

 

Meet the featured startups!

Startups presenting at the Pitch and Pour event represented a cross-section of South Florida’s innovation economy – from media to upskilling, and everything in between. 

Modern Trials – Leveraging electronic medical record data from a broad network of healthcare organizations to match patients in need of advanced treatment options with appropriate clinical trial opportunities.

Streann Media – SaaS platform that enables content providers to build their own distribution platforms. Read more about Streann Media in our member spotlight.

Roomaters – A startup that aims to make it easier to find roommates. Now building a communications platform focused on student housing.

Boca Code – A Boca Raton-based coding school, aiming to help connect budding technologists with some of South Florida’s most exciting tech firms.

Guiltless To Go – An app that provides the delivery of food for people with specific dietary needs.

Best Candidate – An election candidate search engine and campaign media manager.

Parkquility – Taking the headache out of parking by enabling consumers to reserve parking spots in advance. 

Brain A.C.T.I.V.E. – Empowering businesses to improve their employees’ mental fitness.

 

A resounding success, and more to come

Mike Maniscalco, EVP of Technology at Applied Blockchain and Chair of Tech Hub’s Startup Founders Peer Group, underscored the importance of events like the Pitch and Pour for South Florida’s rapidly-expanding tech ecosystem.

“It was an incredibly successful first event,” Maniscalco told South Florida Tech Hub. “We need to do more. It was clear from the amount of attendees that the appetite is huge. We should keep having more of these events, as people continue to be willing to come.”

This event is what the Startup Founders Peer Group is all about: bringing founders and entrepreneurs together to connect, share, and learn from each other in a safe setting. They typically meet once a month to share our successes, needs and resources. Through the work of the Startup Committee, participants attend events such as pitch clinics, contests, and investor connection events. They also hear from guest speakers and take part in summits and expos.

Serial entrepreneur and RaiseLink chief executive Chris Houghtaling was one of the experts hearing pitches at the event. Houghtaling said that he had been to similar events in other tech ecosystems internationally, but nothing quite like it in South Florida.

“Not only did it help startups improve their pitches, but it also allowed for ample networking in a relaxed and fun atmosphere,” commented Houghtaling.

 

Developing South Florida’s tech ecosystem

South Florida Tech Hub is the only tech ecosystem development organization active throughout our region, including Miami-Dade, Broward, Palm Beach, and Martin counties. Through its events, committees, and advocacy, Tech Hub is at the forefront of developing South Florida as a cutting-edge, inclusive hotspot for innovation.

As South Florida rises to prominence on a global stage, events like Pitch and Pour are critical to bring together innovators from the entire region – uplifting all parties while also fostering a strong sense of community.

Tech Hub’s Startup Committee proudly supports and connects dozens of startup organizations and stakeholders in South Florida. It unites the following resources and leaders together to achieve common goals: Startup Accelerators & Incubators, Entrepreneur Support Organizations, Community-oriented Coworking Spaces, Venture Capital & Angel Investors, Economic Development & Government Partners, Corporate & University Innovation Programs and more.

Click here to view more photos from the Pitch & Pour startup event. 📸

 

Are you interested in getting involved in Tech Hub’s activities in South Florida? Come out and show your supPOURt! Visit TechHubSouthFlorida.org or email team@techhubsouthflorida.org for more information. 

By Nikki Cabus

Miami startup Modern Trials wins IDEA Showcase for investment from Seedfunders

Read Time 4 Minutes

Modern Trials, a Miami-based startup, pitched at this year’s IDEA Showcase held on Thursday, June 23rd at the Broward County Convention Center. The startup took home first place which included an investment opportunity with Seedfunders, a Florida-based investment firm.

The HIPAA-compliant platform, Modern Trials, leverages electronic medical record data from a broad network of healthcare organizations to match patients in need of advanced treatment options with appropriate clinical trial opportunities.

IDEA Showcase is part of the #TECHSUPERSHOW at the ITEXPO which has been coming to South Florida for decades. South Florida Tech Hub has been partnering with the expo for three years now. The IDEA Showcase pitch contest has become one of the most popular and best-attended events at the ITEXPO. It features cool startup pitches and networking with open bar.

ITEXPO and the collocated events that comprise the #TECHSUPERSHOW all feature educational sessions presented by industry-leading experts. Attendees also gain valuable new insight from keynotes presented by thought-leaders from around the globe. The expo floor is filled with more than 200 companies demonstrating the latest innovations in a marketplace setting.

Startups that pitched included CERA, Envonics, flo-ops, Modern Trials, Nebulai, Unitii, and In My Team. Six of the seven startups to pitch were from South Florida and for the first time ever a prize package including an investment opportunity. Modern Trials took home the judges prize!

“Despite 20 years of experience and many friends in the [healthcare and clinical trials] industry, I was not able to find an appropriate trial for my own mother,” said Dr. Christopher Ochner, Co-Founder of Modern Trials whose mother was diagnosed with a stage IV glioma. “I came to the startling realization that there exists no way for patients in need to gain access to appropriate clinical trial opportunities.”

Immediately after his mother’s passing, he circled back with his Co-Founder, Dr. Alex Logsdon and said; “you were right; this system is broken and we need to fix it”. After countless hours working through a modernized process flow with regulatory experts, legal counsel and consultants, Modern Trials was born.

The IDEA Showcase judges panel included Tahl Milburn, former tech executive and founder from Silicon Valley turned investor, Danielle Mousseau, Manager of 35 Mules, Florida Power & Light’s Company’s (FPL) innovation hub, Akshay Sharma, former Gartner Analyst having authored or co-authored over 280 research notes and current CTO at Kovair, Ariana Pareja, startup founder with three exits and current President and Co-founder at Pareja Family Foundation which provides tech bootcamp scholarships for women and minorities, and Dave Chitester, Founder of Florida Funders, Founder of Seedfunders, and named one of Florida Trend’s 500 Most Influential Business Leaders in the state.

Dave Chister announced the judges winner and awarded Modern Trials with a minimum of $5000 investment through his firm Seedfunders. He said that after due diligence the investment could be much more significant. South Florida Tech Hub also added a free Startup level membership for Modern Trails for one full year.

Seedfunders is investing in pre-revenue scalable technology throughout the state of Florida. Led by a group of leading visionaries, Seedfunders is paving the way for technology startups throughout the state with a presence in St. Petersburg, Orlando and Miami. Dave recently moved to Miami to be able to support startups across the entire South Florida region.

With a unique focus on pre-revenue stage concepts, Seedfunders brings a different approach with mentoring and guidance for developing an MVP and bringing your concept to market.

“No question that cash is the lifeblood of every startup, particularly given the current economic environment,” said Modern Trials Co-Founder Dr. Ochner. “To us, however, an investment from SeedFunders means much more than that. Good mentorship is even more valuable than cash and the intellectual investment that Dave Chitester and his group make in the companies they chose to work with is the real prize.”

With approximately 200 people in attendance for the IDEA Showcase, there was an audience winner chosen as well. The audience used a real-time voting tool to choose their favorite pitch and the winner was CERA – Critical Emergency Response Applications.

Judge and investor, David Chister assured a handful of the startups that pitched that they were close behind, He urged each of them to apply for investment from Seedfunders as well.

Click here for more info on Seedfunders, Modern Trials, CERA and the ITEXPO.

 

 

 

A Small Startup with Big Backing is Betting it can Fix Clinical Trials and has Issued a Challenge to Find Out
Modern Trials and InterSystems Collaborate to Transform Clinical Trial Recruitment
FAU Tech Runway announces Venture Class 11 companies
Entrepreneurs and investors come together at sold-out Pitch and Pour event in Coral Gables
Miami startup Modern Trials wins IDEA Showcase for investment from Seedfunders